Know your medicine one dose at a time! By Dr Manish Bothale
Mechanism of action
Insulin Degludec is ultra-long acting basal insulin which provides 24 to 48 hr basal insulin coverage as compared to the others. Insulin Degludec, is available in two strengths: 100 units/ml and 200 units/ml. Insulin Degludec also has the ability to be mixed with other insulins, thereby improving glycaemic control. It has a flexible, three times a week dosing regimen that can be administered at any time of the day.
It is administered by a subcutaneous injection only.
The advantages of Insulin Degludec are-
It may result in hypoglycemia (but it has a very low incidence rate as compared to other available insulin)
May be used
Adults who have Diabetes (both Type 1 and Type 2 Diabetes) may use Insulin Degludec. It is also useful for people who have glycaemic variability.
Should not be used by
Dr Manish Bothale is Consultant Diabetologist at Chellaram Diabetes Institute in Pune