People with Diabetes have an increased risk of becoming seriously ill or dying from COVID-19. Researchers have found a link between lower levels of a small molecule in people with Diabetes and the risk of developing severe COVID-19. The study showed that supplements of 1,5-AG, a blood biomarker for human Diabetes, could reduce replication of the coronavirus in mice.
In experiments on mice, researchers found that mice treated with 1,5-AG had milder COVID-19 and less severe lung damage than the control group. The researchers concluded that 1,5-AG deficiency led to for severe Sars-CoV-2 pathogenesis in diabetic mice. Sustained supplementation of 1,5-AG to a normal level in diabetic mice lowered severity of COVID-19. The implications of this research are still being studied.
Research is on-going to successfully produce 1,5-AG supplement in slow-release capsules. Till such a capsule was available. people with Diabetes could eat foods rich in 1.5-AG. such as soybeans.